The topoisomerases I are referred to such a group of enzymes that serves the role of cutting one of the strands of the DNA that exists in the form of double-helical structure. Moreover, they have the ability to relax the strand by removing the coiling and also to reanneal the strands. This class of enzymes is further subdivided into type IA and type IB.
Both these types are structurally as well as mechanistically different from each other. The type IA tends to relax the negative supercoiling of the DNA in the case of prokaryotes. On the other hand, topo IB is responsible for introducing positive supercoils, for separating the genetic material of the daughter cells after replication, and for altering the linking number by the multiple of one.
Meiotic nondisjunction is much more likely than mitotic nondisjunction. Based on
A woman who is heterozygous, Bb, has brown eyes;
Explain why familial breast cancer shows a dominant pattern of inheritance in
How is an F′ factor different from an F factor?
With regard to the timing of conjugation, explain why the recipient
The raw material for evolution is random mutation. Discuss whether or
Why is an antibody used in this experiment? From
Explain the type of speciation (allopatric, parapatric, or sympatric
In fruit flies, curved wings are recessive to straight wings,
A recessive allele in mice results in an unusally long neck.
