Questions from Organic Chemistry

Q: Tertiary amines with three different alkyl groups are chiral but cannot be

Tertiary amines with three different alkyl groups are chiral but cannot be resolved because pyramidal inversion causes racemization at room temperature. Nevertheless, chiral aziridines can be resolved...

Q: Lidocaine is one of the most widely used local anesthetics. Draw

Lidocaine is one of the most widely used local anesthetics. Draw the form of lidocaine that is expected to predominate at physiological pH.

Q: Propose a mechanism for the following transformation: /

Propose a mechanism for the following transformation:

Q: When aniline is treated with fuming sulfuric acid, an electrophilic aromatic

When aniline is treated with fuming sulfuric acid, an electrophilic aromatic substitution reaction takes place at the meta position instead of the para position, despite the fact that the amino group...

Q: para-Nitroaniline is an order of magnitude less basic than metanitroaniline

para-Nitroaniline is an order of magnitude less basic than metanitroaniline. a. Explain the observed difference in basicity. b. Would you expect the basicity of ortho-nitroaniline to be closer in va...

Q: Draw the product obtained when each of the following compounds is heated

Draw the product obtained when each of the following compounds is heated in the presence of a base to give an aldol condensation:

Q: Methadone is a powerful analgesic that is used to suppress withdrawal symptoms

Methadone is a powerful analgesic that is used to suppress withdrawal symptoms in the rehabilitation of heroin addicts. Identify the major product that is obtained when methadone is subjected to a Hof...

Q: In general, nitrogen atoms are more basic than oxygen atoms.

In general, nitrogen atoms are more basic than oxygen atoms. However, when an amide is treated with a strong acid, such as sulfuric acid, it is the oxygen atom of the amide that is protonated, rather...

Q: Propose a synthesis for each of the following transformations: /

Propose a synthesis for each of the following transformations:

Q: Draw a mechanism for the last step of the Gabriel synthesis,

Draw a mechanism for the last step of the Gabriel synthesis, performed under basic conditions.