Definition of Inversion

Inversion is a rearrangement in the structure of the chromosome. Generally, a segment of the chromosome is reversed end to end. This phenomenon occurs when the chromosome has undergone the process of breakage and rearrangement within itself. There are two kinds of inversions i.e. paracentric and pericentric. In paracentric inversions, the centromere is not involved and the arm of the chromosome suffers from two breaks.


On the other hand, the centromere is involved in pericentric and both the arms have breakpoints. No abnormalities are being caused by inversions unless there is no extra or missed DNA. Inversion just involves the rearrangement of the linear gene sequence and no genetic information is lost.

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