Questions from Genetics

Q: What does a suppressor mutation suppress? What is the difference between

What does a suppressor mutation suppress? What is the difference between an intragenic and an intergenic suppressor?

Q: How would each of the following types of mutations affect protein function

How would each of the following types of mutations affect protein function or the amount of functional protein that is expressed from a gene? A. Nonsense mutation B. Missense mutation C. Up promote...

Q: X-rays strike a chromosome in a living cell and ultimately

X-rays strike a chromosome in a living cell and ultimately cause the cell to die. Did the X-rays produce a mutation? Explain why or why not.

Q: Lactose permease is encoded by the lacY gene of the lac operon

Lactose permease is encoded by the lacY gene of the lac operon. Suppose a mutation occurred at codon 64 that changed the normal glycine codon into a valine codon. The mutant lactose permease is unable...

Q: Is each of the following mutations a silent, missense, nonsense

Is each of the following mutations a silent, missense, nonsense, or frameshift mutation? The original DNA strand is 5′–ATGGGACTAGATACC–3′. (Note: Only the coding strand is shown; the first codon is me...

Q: A point mutation occurs in the middle of the coding sequence for

A point mutation occurs in the middle of the coding sequence for a gene. Which types of mutations—silent, missense, nonsense, and frameshift—would be most likely to disrupt protein function and which...

Q: If a mutation prevented IRP from binding to the IRE in the

If a mutation prevented IRP from binding to the IRE in the ferritin mRNA, how would the mutation affect the regulation of ferritin synthesis? Do you think there would be too much or too little ferriti...

Q: In Chapters 12 through 16, we discussed many sequences that are

In Chapters 12 through 16, we discussed many sequences that are outside a coding sequence but are important for gene expression. Look up two of these sequences and write them out. Explain how a mutati...

Q: Describe the similarities and differences between homologous recombination involving sister chromatid exchange

Describe the similarities and differences between homologous recombination involving sister chromatid exchange (SCE) and that involving homologs. Would you expect the same types of proteins to be invo...

Q: The molecular mechanism of SCE is similar to homologous recombination between homologs

The molecular mechanism of SCE is similar to homologous recombination between homologs except that the two segments of DNA are sister chromatids instead of homologous chromatids. If branch migration o...