Definition of Genotype Environment Interaction

Genotype environment interaction is also known as gene-environment interaction and it is defined as a phenomenon which takes place when the environment affects the phenotype according to the genotype in a varied way. The expression of the trait is due to the interplay between the genotype and the environmental factors. There are some phenotypes that are highly affected by the genes whereas some are highly influenced by the environment.


This interaction between the genotype and the environment is important in genetic epidemiology. The individuals that have different genotypes, they are influenced in a different way by the same environmental factors e.g. the risk of skin cancer that is caused by the exposure of sunlight is greater in fair-skinned individuals as compared to the darker ones.


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