Glucocorticoid receptor is a type of receptor which is a steroid in nature and serves the purpose of a regulatory transcription factor. These receptors are extremely effective in reducing the inflammation and in suppressing the immune system. Our bodies respond to several harmful substances by activating the inflammatory responses and this is actually the part of healing.
But if the mechanisms that turn the inflammation off become dysfunctional, then they can damage the tissues. This continuous inflammation can be a reason for a number of chronic diseases such as obesity, cancer, diabetes, CVDs etc. These are secreted in response to stress from the adrenal glands that are present on the top of the kidneys. They can also be used in order to treat conditions like arthritis, asthma, allergies, lupus etc.
The glucocorticoid receptor and the CREB protein are two examples of transcriptional
Transcription factors such as the glucocorticoid receptor and the CREB protein form
Describe the steps that need to occur for the glucocorticoid receptor to
Let’s suppose a mutation in the glucocorticoid receptor does not prevent the
Explain why the glucocorticoid receptor binds next to the core promoter of
As described in Chapter 15 (Figures 15.7 and 15
