Haploinsufficiency is the phenomenon in which there is only one copy of a gene is present in a person that is potentially functional. This single functional copy of the gene is unable to give rise to a normal phenotype and hence haploinsufficiency shows the dominant pattern of inheritance.
The variant allele may have suffered from the loss of function mutation during inheritance or has arisen from a de novo mutation. This allele produces a very little or no product at all. On the contrary, the other allele produces the normal amount of product but the collective product is not enough to give the standard phenotype.
How is an F′ factor different from an F factor?
Meiotic nondisjunction is much more likely than mitotic nondisjunction. Based on
In fruit flies, curved wings are recessive to straight wings,
What is an advantage and a disadvantage of this repair system?
Explain the type of speciation (allopatric, parapatric, or sympatric
The raw material for evolution is random mutation. Discuss whether or
With regard to the timing of conjugation, explain why the recipient
A woman who is heterozygous, Bb, has brown eyes;
A recessive allele in mice results in an unusally long neck.
Why is an antibody used in this experiment? From