Locus heterogeneity is a phenomenon in which the mutations in two or more than two different genes may cause a certain type of disease. This happens when the mutations present at various loci have the tendency to produce a single trait and hence the same phenotype and these mutations can independently cause a specific phenotype.
Locus heterogeneity is associated directly with a number of diseases caused in humans such as retinitis pigmentosa, familial hypercholesterolemia, etc. The role of this heterogeneity aids in the development of therapeutics for the diseases. Genetic mapping cannot be used in the detection of the loci hence the techniques have been modified to overcome such challenges.
Meiotic nondisjunction is much more likely than mitotic nondisjunction. Based on
A woman who is heterozygous, Bb, has brown eyes;
Explain why familial breast cancer shows a dominant pattern of inheritance in
How is an F′ factor different from an F factor?
With regard to the timing of conjugation, explain why the recipient
The raw material for evolution is random mutation. Discuss whether or
Why is an antibody used in this experiment? From
Explain the type of speciation (allopatric, parapatric, or sympatric
In fruit flies, curved wings are recessive to straight wings,
A recessive allele in mice results in an unusally long neck.
