Definition of Long Non Coding



Long non-coding RNA is also known as incRNA is a non-coding RNA that is composed of more than 200 nucleotides in its molecule. They belong to the varied class of transcribed RNA molecules that do not have the ability to encode protein molecules. They account for approximately 30,000 variable transcripts in human beings. In this way, these lncRNA constitute the pivotal part of the non-coding transcriptome.

 


They are transcribed to coding genes as a whole or through natural antisense transcripts. They are thought to be located between the genes or in the introns. The lncRNAs are classified into antisense, intergenic, overlapping, intronic, bidirectional, and processed subtypes. These are involved in cellular and developmental functions.


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