Malonic ester synthesis is the type of chemical reaction in which either diethyl malonate or any other malonate ester is alkylated. The alkylation takes place at the α- carbon. This carbon can be deprotonated by a strong base and this carbanion formed then undergoes nucleophilic substitution on the alkyl halide to form an alkylated compound.
This alkylation process leads to the conversion of an ester of malonic acid into carbonyl groups which are then converted into acetic acid. The yield of such kind of reaction is notably low as the alkylation step produces unwanted dialkylated structures and in this way, the separation of products becomes difficult.
Draw and name four terminal alkynes with the molecular formula C6H10.
Report the result of the following addition to the proper number of
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Write an equation for the proton transfer reaction that occurs when each
87. What is the major product of this reaction?
Propose a stepwise mechanism for the following transformation: /
Identify the sole product of the following reaction: /
Draw the condensation product that is expected when each of the following
Draw a mechanism for each of the following transformations: /
Draw each of the following using condensed formulas and line formulas: