Mitotic recombination is the crossing over of the chromosomes that results in the formation of a pair of recombinant chromosomes. It occurs in somatic cells when the cells are getting themselves prepared for mitosis. Mitotic recombination takes place in both sexual and asexual organisms. It occurs during the preparatory phase of cell cycle i.e. interphase.
It has been determined that this recombination of genes take place during G1 phase. In this phase, the DNA is in its 2-strand phase. The mitotic recombination produces gene expression of recessive traits in a heterozygous organism. The recessive genes and the formation of tumors have been studied through such an expression. This recombination prominently occurs between the two sister chromatids prior to cell division.
Meiotic nondisjunction is much more likely than mitotic nondisjunction. Based on
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