Definition of Monoallelic Expression

The monoallelic expression is a gene expression in which out of two copies (alleles) of a gene, only one gets activated whereas the other remains unexpressed or is silenced. This expression of genes gets initiated as early as an organism has started developing and is maintained throughout life. Researches are being done in order to determine whether which genes are displaying a monoallelic expression.



The expression of those genes is more prevalent which are bi-allelic. In this case, both the alleles of that particular gene are transcribed and translated. On the contrary, a very small number of genes depict monoallelic expression and the allele that is expressed is determined by the parent such as in imprinting.

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