A palindromic sequence is referred to such a nucleic acid sequence which is present in the complementary strands of the double-stranded DNA or RNA in which the sequence present in one strand in a certain direction is same as that of the sequence present in the same direction on the complementary strand.
It is mandatory that the direction of both the strands should be 5’ to 3’ or 3’ to 5’. Hence, we can say that the sequences are palindromic if they are complementary to each other in the reverse order. The sequence of a palindromic nucleotide has a capability of forming a hairpin loop.
Example of Palindromic:
The sequence of DNA ACCTAGGT is palindromic as its complementary sequence is TGGATCCA. When its order is reversed, it gives us the original sequence.
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