Questions from Genetics


Q: An experimenter used primers that recognize nine different STSs to test their

An experimenter used primers that recognize nine different STSs to test their presence in five different BACs. The results are shown here. Draw a contig that maps the alignment of the five BACs.

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Q: In the Human Genome Project, researchers have collected linkage data from

In the Human Genome Project, researchers have collected linkage data from many crosses in which the male was heterozygous for molecular markers and many crosses where the female was heterozygous for t...

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Q: Take a look at question 3 in More Genetic TIPS. Let’s

Take a look at question 3 in More Genetic TIPS. Let’s suppose a male is heterozygous for two polymorphic sequence-tagged sites. STS-1 exists in two sizes: 211 bp and 289 bp. STS-2 al...

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Q: Place the following stages of a physical mapping study in their most

Place the following stages of a physical mapping study in their most logical order: A. Clone large fragments of DNA to make a BAC library. B. Determine the DNA sequence of subclones from a cosmid li...

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Q: What is an STS? How are STSs generated experimentally? What

What is an STS? How are STSs generated experimentally? What are the uses of STSs? Explain how a microsatellite can be a polymorphic STS.

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Q: In an in situ hybridization experiment, what is the relationship between

In an in situ hybridization experiment, what is the relationship between the base sequence of the probe DNA and the site on the chromosomal DNA where the probe binds?

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Q: Discuss where protists are found in this newer organization of eukaryotic species

Discuss where protists are found in this newer organization of eukaryotic species.

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Q: Explain what happened to the b allele that allowed gene conversion to

Explain what happened to the b allele that allowed gene conversion to occur.

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Q: Describe the technique of in situ hybridization. Explain how it can

Describe the technique of in situ hybridization. Explain how it can be used to map genes.

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Q: The cells from a person’s malignant tumor were subjected to in situ

The cells from a person’s malignant tumor were subjected to in situ hybridization using a probe that recognizes a unique sequence on chromosome 14. The probe was detected only once in each of the cell...

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