Questions from Genetics

Q: Discuss the bioinformatics approaches that can be used to identify a protein

Discuss the bioinformatics approaches that can be used to identify a protein-encoding gene.

Q: What is a motif? Why is it useful for computer programs

What is a motif? Why is it useful for computer programs to identify functional motifs within amino acid sequences?

Q: Discuss why it is useful to search a database to identify sequences

Discuss why it is useful to search a database to identify sequences that are homologous to a newly determined sequence.

Q: In this chapter, we considered a computer program that can translate

In this chapter, we considered a computer program that can translate a DNA sequence into a polypeptide sequence. A researcher has a sequence file that contains the amino acid sequence of a polypeptide...

Q: Researchers have used the cloning methods described in Chapter 21 to clone

Researchers have used the cloning methods described in Chapter 21 to clone the bicoid gene and express large amounts of the Bicoid protein. The Bicoid protein was then injected into the posterior end...

Q: Two techniques commonly used to study the expression patterns of genes that

Two techniques commonly used to study the expression patterns of genes that play a role in development are Northern blotting and in situ hybridization. As described in Chapter 21, Northern blotting is...

Q: Explain one experimental strategy for determining the functional role of the mouse

Explain one experimental strategy for determining the functional role of the mouse HoxD-3 gene.

Q: Which RNA conformation favors transcription—the form with the antiterminator stem

Which RNA conformation favors transcription—the form with the antiterminator stem-loop or the form with the terminator stem-loop?

Q: In the experiment of Figure 26.16, suggest reasons why

In the experiment of Figure 26.16, suggest reasons why the n536, n355, and n540 strains have an egg-laying defect From Figure 26.16: Answer: An egg-laying defect is somehow related to an abnormal an...

Q: Another way to study the role of proteins (e.g

Another way to study the role of proteins (e.g., transcription factors) that function in development is to microinject the mRNA that encodes a protein, or the purified protein itself, into an oocyte o...