2.99 See Answer

Question: Each human gene is encoded as deoxyribonucleic


Each human gene is encoded as deoxyribonucleic acid (DNA), which takes the shape of a “double helix.” Each “cross-bar” in that helix consists of two chemically joined nucleotides. Sequences of DNA nucleotides contain the information necessary to create strings of amino acids used to build proteins in the body. The nucleotides that code for amino acids are “exons,” and those that do not are “introns.” Scientists can extract DNA from cells to isolate specific segments for study. They can also synthetically create exons-only strands of nucleotides known as complementary DNA (cDNA). cDNA contains only the exons that occur in DNA, omitting the intervening introns.
Respondent Myriad Genetics, Inc. (Myriad), obtained several patents after discovering the precise location and sequence of the BRCA1 and BRCA2 genes, mutations of which can dramatically increase the risk of breast and ovarian cancer. This knowledge allowed Myriad to determine the genes’ typical nucleotide sequence, which, in turn, enabled it to develop medical tests useful for detecting mutations in these genes in a particular patient to assess the patient’s cancer risk. If valid, Myriad’s patents would give it the exclusive right to isolate an individual’s BRCA1 and BRCA2 genes, and would give Myriad the exclusive right to synthetically create BRCA cDNA. Petitioners filed suit, seeking a declaration that Myriad’s patents are invalid under 35 U. S. C. §101. As relevant here, the District Court granted summary judgment to petitioners, concluding that Myriad’s claims were invalid because they covered products of nature. The Federal Circuit initially reversed, but on remand in light of Mayo Collaborative Services v. Prometheus Laboratories, Inc., 566 U. S.___, the Circuit found both isolated DNA and cDNA patent eligible.
Held
A naturally occurring DNA segment is a product of nature and not patent eligible merely because it has been isolated, but cDNA is patent eligible because it is not naturally occurring. (a) The Patent Act permits patents to be issued to “[w]hoever invents or discovers any new and useful . . . composition of matter,” §101, but “laws of nature, natural phenomena, and abstract ideas” “‘are basic tools of scientific and technological work’” that lie beyond the domain of patent protection, Mayo, supra, at ___,. The rule against patents on naturally occurring things has limits, however. Patent protection strikes a delicate balance between creating “incentives that lead to creation, invention, and discovery” and “imped[ing] the flow of information that might permit, indeed spur, invention.” Id., at __. This standard is used to determine whether Myriad’s patents claim a “new and useful . . . composition of matter,” §101, or claim naturally occurring phenomena.
(b) Myriad’s DNA claim falls within the law of nature exception. Myriad’s principal contribution was uncovering the precise location and genetic sequence of the BRCA1 and BRCA2 genes. Diamond v. Chakrabarty, 447 U. S. 303, is central to the patent-eligibility inquiry whether such action was new “with markedly different characteristics from any found in nature,” id., at 310. Myriad did not create or alter either the genetic information encoded in ………………………….

Required:
1. What is cDNA?
2. Why is cDNA patentable, while DNA is not?


> What was the Court’s holding in Powell v. Alabama? See the Gideon v. Wainwright case in this chapter.

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> Explain how section 1139 found in Figure 4-2 might be used in the Welsh case.

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> Should U.S. district court judges be appointed by the president, or should they be elected by the people in the district where they serve?

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> Petitioners brought suit against respondent after a catheter ruptured in the patient’s coronary artery during surgery, killing him. The catheter received “premarket” approval from the FDA pursuant to a federal law regulating medical devices. The law proh

> Discuss the relationship between case law and statutory law as illustrated in the case of United States v. Playboy Entertainment Group, Inc., found in Appendix VII.

> A conflict between state and federal criminal law arose in the case of United States v. Oakland Cannabis Buyers Cooperative, found in Appendix VII. Explain how the court resolves the problem.

> Three young men were assaulted because of their race. The assailant was arrested and charged with several offenses, including assault with a firearm, civil rights violations and brandishing a weapon. Was the civil rights violation civil or criminal? Expl

> Harvey Lee Windsor was convicted of capital murder under § 13A-5–40(a) (2), Ala. Code 1975, and was sentenced to death by electrocution. Windsor appealed the conviction and sentence to the Court of Criminal Appeals. That court reversed the conviction and

> Just sit right back and you’ll hear a tale” of what happened when David Reuther, while vacationing in the Cayman Islands at the Pirates Point Resort Hotel, decided to go scuba diving—“a fateful trip that started from this tropic port, aboard this tiny sh

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> After his 2009 arrest on first- and second-degree assault charges, respondent King was processed through a Wicomico County, Maryland, facility, where booking personnel used a cheek swab to take a DNA sample pursuant to the Maryland DNA Collection Act (Ac

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> Facts On September 13, 1981, Kenneth Roy and one Jesse McHargue, while hitchhiking near Gridley, California, met Archie Mannix and James Clark outside a liquor store and began drinking beer with them. A Gridley police officer observed the foursome in a p

> Justice Sotomayor delivered the opinion of the Court When the State of Michigan rested its case at petitioner Lamar Evans’ arson trial, the court entered a directed verdict of acquittal, based upon its view that the State had not provided sufficient evid

> In the late 1980s, petitioner Major League Baseball Players Association (Association) filed grievances against the Major League Baseball Clubs (Clubs), claiming the Clubs had colluded in the market for free-agent services after the 1985, 1986 and 1987 ba

> Justice Scalia delivered the opinion of the Court. We consider whether a contractual waiver of class arbitration is enforceable under the Federal Arbitration Act when the plaintiff ’s cost of individually arbitrating a federal statutory claim exceeds the

> The petitioner is a well-known entertainer in the television industry. The respondent is a “personal manager” in the entertainment profession. On January 16, 1974 they signed a contract whereby the petitioner agreed to employ the respondent as his agent

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> Justice Breyer delivered the opinion of the Court. The federal diversity jurisdiction statute provides that “a corporation shall be deemed to be a citizen of any State by which it has been incorporated and of the State where it has its principal place o

> KOZINSKI, Chief Judge: You don’t need a peg leg or an eye patch. When you ram ships; hurl glass containers of acid; drag metal-reinforced ropes in the water to damage propellers and rudders; launch smoke bombs and flares with hooks; and point high-powere

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> When this case was at issue, we referred it to retired Circuit Judge P. B. Revels of the Seventh Judicial Circuit, one of Florida’s most experienced trial judges, to serve as referee. The referee has filed his report which, in pertinent part, indicates:

> The Oakland Raiders (hereafter, Raiders) football club has sued the National Football League (hereafter, NFL), 16 NFL clubs, and many other NFL-related persons and entities, generally alleging that NFL leadership has been marked by abuse of power, neglec

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> CHIEF JUSTICE ROBERTS delivered the opinion of the Court. The public is currently engaged in an active political debate over whether same-sex couples should be allowed to marry. That question has also given rise to litigation. In this case, petitioners,

> The question, whether an act, repugnant to the constitution, can become the law of the land, is a question deeply interesting to the United States. That the people have an original right to establish, for their future government, such principles as, in t

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> Consider the following two examples and determine whether each is criminal or civil. Foreman drives a car (somewhat ineffectively) after consuming five martinis in one hour. Foreman is not involved in any accident and no one is injured as a result of the

> At age 17, respondent Simmons planned and committed a capital murder. After he had turned 18, he was sentenced to death. His direct appeal and subsequent petitions for state and federal post-conviction relief were rejected. This Court then held, in Atki

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> Read the excerpt of the case, Tennessee v. Garner in Appendix VII. Answer the following questions: a. Which constitutional provisions apply to this case and how do they apply? b. What statutory law is the Court interpreting in this case? c. Did the Court

> Locate the following cases. For each, write the correct citation, including the year. You may use an online source such as Findlaw, or you may locate the cases in a print resource in a law library. 491 U.S. 274 372 U.S. 335 367 U.S. 643 384 U.S. 436 474

> Review the Modnick case. As you read, identify the facts, the issues, the rules or laws, the holding, and the conclusion. Notice how the court explains or analyzes in this decision. Refer back to the Welch case at the beginning of the chapter. Identify e

> Peter, Paul, and Mary are 16-year-olds who live in Elmwood, a city with a 10 p.m. curfew for anyone under the age of 18. They think the law is unfair and violates their constitutional rights, and they want it changed. How can they go about doing this? (R

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> MR. JUSTICE DOUGLAS delivered the opinion of the Court. Appellant Griswold is Executive Director of the Planned Parenthood League of Connecticut. Appellant Buxton is a licensed physician and a professor at the Yale Medical School who served as Medical Di

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> Read the following hypothetical situation after reviewing the Case File at the beginning of this chapter. Focus on the statements that may be hearsay. Tommy Rutherford and his family were staying at the lake for the summer. Tommy’s family has a very smal

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> Discuss the differences between the complaints in the Simpson and Nichols cases.

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> Lawrence hired a law firm to represent him in a legal matter and signed an agreement containing a provision requiring arbitration in the event of any dispute regarding fees, costs, or any other aspect of the attorney-client relationship. Eventually Lawre

> Read the case Good News Club v. Milford Central School found in Appendix VII. What was the nature of the lawsuit filed in the trial court? What happened in the trial court?

> A car dealership in Ohio used the image of a famous celebrity residing California in an Internet web site promoting the car dealership. The dealership did not have permission to use the image. Cars were not sold through the Web site. The celebrity sued t

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> Reread the facts of Kaplan. In this case, the appellate court did not find that Coldwell Banker was an ostensible agent, only that there were sufficient facts to withstand a summary judgment (a declaration by the court that there were no facts to support

2.99

See Answer