Questions from Genetics


Q: What are the roles of Cas1, Cas2, and Cas9 proteins

What are the roles of Cas1, Cas2, and Cas9 proteins in bacterial genome defense?

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Q: Outline the steps that occur when piRISCs silence transposable elements by repressing

Outline the steps that occur when piRISCs silence transposable elements by repressing transcription and by directly inhibiting TE RNAs. What is the role of piRNAs in this process?

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Q: List five types of cancer in which ncRNAs can be involved.

List five types of cancer in which ncRNAs can be involved.

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Q: Explain how the miR-200 family of miRNAs behave as tumorsuppressor

Explain how the miR-200 family of miRNAs behave as tumorsuppressor genes. What happens when their expression is blocked or decreased?

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Q: Explain how the VIN3/PRC2 complex specifically binds to the FLC

Explain how the VIN3/PRC2 complex specifically binds to the FLC gene.  

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Q: What is a histone variant?

What is a histone variant?

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Q: Explain how the acetylation of core histones may loosen chromatin packing.

Explain how the acetylation of core histones may loosen chromatin packing.

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Q: What are the two ways in which piRNAs and PIWI proteins prevent

What are the two ways in which piRNAs and PIWI proteins prevent the movement of transposable elements?

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Q: An ncRNA may have the following functions: scaffold, guide,

An ncRNA may have the following functions: scaffold, guide, alterer of protein function or stability, ribozyme, blocker, and/or decoy. Which of those functions is/are mediated by each of the ncRNAs li...

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Q: What is meant by the term histone code? With regard to

What is meant by the term histone code? With regard to gene regulation, what is the proposed role of the histone code?

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